3 Final Report on the Safety Assessment of Benzethonium ... Benzalkonium Chloride SDS Safety Data Sheet MSDS Sheet, Material Safety Data Sheet 02-Oct-20. The CIR Expert Panel evaluated scientific data and concluded that Benzalkonium Chloride, at concentrations up to 0.1% free, active ingredient, was safe as a cosmetic ingredient. Commission regulation (EU) no. Close. Uses advised against Not for food, drug, pesticide or biocidal product … SAFETY DATA SHEET According to JIS Z 7253:2019 Version 2.02 Revision Date 16-Sep-2021 Section 1: PRODUCT AND COMPANY IDENTIFICATION Product name 10% Benzalkonium Chloride Solution Product code 028-05466 Manufacturer FUJIFILM Wako Pure Chemical Corporation 1-2 Doshomachi 3-Chome What is benzalkonium chloride? For most multidose aqueous nasal, ophthalmic and otic products, benzalkonium chloride is the preservative of choice. They can be do not inhale or ingest. Benzalkonium Chloride is sold commercially as 50.0% or 80.0% solutions in water or alcohol, or in mixtures of water, ethyl alcohol, and isopropyl alcohol.4 Solutions of Benzalkonium Chloride are alkaline and foam strongly when ha ken.^ Benzalkonium Chloride, … min for Benzalkonium Chloride-1 and Benzalkonium Chloride-2 and it was found linear (Figure 3). Ideal for. Product Name & Other Names: Benzalkonium Chloride, BZK, BKC, BAC, alkyldimethylbenzylammonium chloride and ADBAC CAS No. Marketing Status: OTC monograph not final. In most test cases, benzalkonium chloride obliterated the virus with 15 seconds, wiping out at least 99.9%. Benzalkonium chloride dissociates into cationic active group in aqueous solution, which has the function of cleaning and sterilization. Benzalkonium chloride, a quaternary ammonium compound, is a mixture of several n-alkylbenzyldimethylammonium chlorides (n = 10–16) with different alkyl groups . Lidocaine HCL 4%. Contains 0.13% Benzalkonium Chloride. 8001-54-5 Benzalkonium Chloride < 1 % 144-55-8 Carbonic acid monosodium salt < 1 % 7732-18-5 Water > 99 % Section 4. Show this safety data sheet to the doctor in attendance. Regular use of products containing antimicrobials such as benzalkonium chloride could leads to the development of resistant bacteria in homes and food processing facilities. Benzalkonium Chloride 5% SAFETY DATA SHEET Date of issue - 24/08/2009. Precautionary statements P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. Benzalkonium chloride is found in many household disinfectants and cleaning supplies. The ingredient is used in cosmetic products as a foaming cleansing and bactericidal agent at concentrations up to 5.0%. We're growing! : 8001-54-5 or 63449-41-2 EINECS EC Code: 264-151-6 Molecular Weight: Variable. Benzalkonium chloride (50% aqueous solution) EMPROVE® EXPERT Ph Eur,NF - Find MSDS or SDS, a COA, data sheets and more information. WebMD: Is the request for more information related to the fact that we have more scientific tools available to understand the absorption rates of these chemicals? Product name : Benzalkonium Chloride 50% Solution CAS-No. Both types are individually foil-wrapped, and measure 8" x 11". Material Safety Data Sheet Product Name Benzalkonium chloride Page 3 of 13 Reduced labelling (≤125 ml) Hazard statements H314 Causes severe skin burns and eye damage. Find patient medical information for benzalkonium chloride on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Not made with natural rubber latex. 2.Benzalkonium chloride belongs to antiseptic medicine. The store will not work correctly in the case when cookies are disabled. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND COMPANY/UNDERTAKING Product name: Application: Supplier: Benzalkonium Chloride 80% (BKC80%) Preservative and active ingredient in the cosmetic and pharmaceutical industries. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION Product Name: Benzalkonium chloride Company Identification: 237/2, Vellivoyal Chavadi Chennai - 600 103. 1. Is Benzalkonium Chloride Safe? Benzalkonium has been in existence for over a century, and is probably the most intensely studied synthetic biocide available to man. Benzalkonium Chloride is a mixture of alkylbenzyldimethylammonium chlorides. An odorless antiseptic compound widely used as a disinfectant in detergents. is contained in products used as plant strengtheners. if skin irritation develops. if skin irritation develops. Active Ingredient. Benzalkonium chloride is primarily used as a preservative and antimicrobial agent. Benzalkonium Chloride Update. The ingredients are stable and less oxidized. Benzalkonium chloride solution ≥50% (via Cl), 50% in H2O; CAS Number: 63449-41-2; Synonyms: Alkylbenzyldimethylammonium chloride; find Sigma-Aldrich-63249 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich : AC263820000; AC263820010; AC263820025 Synonyms Alkyl-benzyl-dimethylammonium chloride Recommended Use Laboratory chemicals. First-Aid Measures General Advice: Take proper precautions to ensure your own health and safety before attempting rescue and providing first aid. Details of the supplier of the safety data sheet The regression equation for the curve was found as y=32468902.34093X-8066.55862 with correlation coefficient (R2) 0.99996. Characteristics 1.1. Keep out of eyes. May cause drowsiness or dizziness. Overview Three broad-spectrum actives, ethanol, isopropanol and benzalkonium chloride (BZK), are allowed under the current FDA OTC Hand Sanitizer monographs for healthcare workers and consumers. Nucleic Acid Extraction. Allergic contact dermatitis (ACD) is a socially and economically significant condition. box) 887 kensington ave. : 63449-41-2 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Industrial & for professional use only. Benzalkonium Chloride is a commonly used preservative in contact lens solutions and can be found as an ingredient in antimicrobial soaps, skin antiseptics, and spermicides. Consult a physician. Product (s): 63449-41-2 Benzalkonium chloride solution 95%. Allergic contact dermatitis (ACD) is a socially and economically significant condition. Category (function) Benzalkonium chloride is a quaternary amm onium antiseptic and disinfectant with actions and uses similar to those of other cationic surfactants. Wash thoroughly after handling. Buy Benzalkonium Chloride Online Here Or By Phone: 512-668-9918. : 8001-54-5 or 63449-41-2 EINECS EC Code: 264-151-6 Molecular Weight: Variable. Tamilnadu Office Telephone No: 044 64606747 2. DSS-Induced Colitis. Manufactured in the US with domestic and foreign materials to the highest quality standards. ; Concentrations of household products vary, often between 0.2-5%. ZEPHIRAN is supplied as a 1:750 aqueous solution, further dilution may European Commission, Brussels, Belgium. At the end of June, the EU Commission approved benzalkonium chloride and didecyldimethylammonium chloride as active substances for the use in biocidal products … Check out our job openings! Since 1935, BAC has been used in a wide variety of products such as disinfectants, preservatives, and sanitizers. Methods Library. Benzethonium chloride is a (synthetic) quaternary ammonium salt that is benzyldimethylamine in which the nitrogen is quaternised by a 2-{2-[p-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethyl group, with chloride as the counter-ion. Personal Precautions, Protective Equipment and Emergency Procedures Apply now! The safety of Benzalkonium Chloride has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. Benzalkonium Chloride. Four tear solutions containing 0.01% benzalkonium chloride (BAC), a formulation containing 0.001% Polyquad, a contact lens re-wetting solution containing 0.004% thimerosal, and each of the above preservatives in balanced salt solution (BSS) were evaluated. 2015;14:619–23. Find Safety Data Sheets(SDS) of BENZALKONIUM CHLORIDE(CAS 68424-85-1 ) for lookchem Latex. When benzalkonium … Causes serious eye irritation. Benzalkonium Chloride Update. Ingestion from grooming after walking over surfaces recently cleaned with a benzalkonium chloride Benzalkonium chloride -containing product (often in household disinfectants, antibacterial cleaners, mold removers, hand sanitizers, patio cleaners, etc). Material Safety Data Sheet Benzalkonium chloride, 50 wt% aqueous solution ACC# 87924 Section 1 - Chemical Product and Company Identification: MSDS Name: Benzalkonium chloride, 50 wt% aqueous solution Catalog Numbers: AC263820000, AC263820010 Expert Opin drug Saf. containing benzalkonium chloride are used for the treatment of superficial inf ections of the mouth and throat [23]. For most multidose aqueous nasal, ophthalmic and otic products, benzalkonium chloride is the preservative of choice. 1119/2014 of 16 October 2014 amending annex III to regulation (EC) no. SAFETY DATA SHEET According to JIS Z 7253:2019 Version 2.02 Revision Date 16-Sep-2021 Section 1: PRODUCT AND COMPANY IDENTIFICATION Product name 10% Benzalkonium Chloride Solution Product code 028-05466 Manufacturer FUJIFILM Wako Pure Chemical Corporation 1-2 Doshomachi 3-Chome Grade: Ph Eur,NF. Benzalkonium chloride, commonly abbreviated as BZK, has wide-spread uses as an antiseptic and disinfectant. DSS-Induced Colitis. The substance is used in disinfectants and detergents. Benzalkonium chloride is both a biocide and a pesticide active substance. Benzalkonium chloride ≥95.0% (T); CAS Number: 63449-41-2; EC Number: 264-151-6; Synonyms: Alkylbenzyldimethylammonium chloride,Alkyldimethylbenzylammonium chloride; Linear Formula: C6H5CH2N(CH3)2RCl (R=C8H17 to C18H37); find Sigma-Aldrich-12060 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich You will need to talk about the benefits and risks of using benzalkonium chloride while you are pregnant. Made in the USA. Get medical attention. Benzalkonium chloride (BKC) is a quaternary ammonium compound that has been in clinical use since 1935 1 as an antimicrobial additive. In addition, DDAC . Product Name & Other Names: Benzalkonium Chloride, BZK, BKC, BAC, alkyldimethylbenzylammonium chloride and ADBAC CAS No. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Benzalkonium Chloride MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. Dosage form: soap Ingredients: BENZALKONIUM CHLORIDE 0.13g in … The US Food and Drug Administration (FDA) specifies that the safe and effective concentrations for benzethonium chloride are 0.1-0.2% in first aid products. Aqueous solutions of benzethonium chloride are not absorbed through the skin. It is not approved in the US and Europe for use as a food additive. Benzalkonium Chloride 0.12%. In Canada, it is a known active ingredient in hard surface disinfectants and hand sanitizers. From benzalkonium chloride-preserved latanoprost to polyquad-preserved travoprost: a 6-month study on ocular surface safety and tolerability. It is widely used in the health care industry and cosmetic industry as an antimicrobial and cleansing agent. (A) Rabbit eye instilled twice a day with one drop of 0.01% benzalkonium chloride (BAK) for 1 and 5 months (Low Chronic model, LCm): two images (separated by a dotted red line) for each model (separated by a red line) showing the BAK distribution using MALDI-TOF mass spectrometry … Report Adverse Events, FDA Safety Recalls, Presence in Breast Milk. Certificates. Do NOT induce vomiting. It can be used as an antiseptic and preservative in personal care, healthcare, household, pharmaceutical, and industrial products [1,2].. What is benzalkonium chloride contact dermatitis?. Choice of a 70% Isopropanol wipe or a non-alcohol wipe with the active ingredient Benzalkonium Chloride. It was used to estimate the amount of Benzalkonium Chloride. Keep out of reach of children. Benzalkonium chloride itself is a mixture of very similar substances with different chain length and molecular mass. Ltd. Glentham Life Sciences Ltd. CAS: 8001-54-5. Molecular Weight: 0.00. Septic systems can handle small amounts of disinfectants, but with the current health concerns related to COVID-19, there are both existing and new products that may be impacting septic systems. A risk assessment of benzalkonium chloride (BAC) was conducted based upon its toxicological profile and exposure evaluation. Benzalkonium chloride is active at low concentrations and has been used to kill bacteria, fungi, Algae, and lichens.It does not kill spores.This type of quaternary ammonium compound has reduced effectiveness in solutions containing hard water, salts, or organic compounds. Background: For most multiuse aqueous nasal, ophthalmic, and otic products, benzalkonium chloride (BKC) is the preservative of choice. Product Identification. This article discusses benzalkonium chloride, within the context of its historical and clinical significance in association with its use in antiseptics, cosmetics, detergents, and topical medications. For the temporary relief of pain and itching associated with: Sunburn, Minor Cuts & Scrapes, Minor Skin Irritation, Minor Burns. In benzalkonium chloride, the common ingredient used in alcohol-free hand sanitizers, and other quaternary ammonium compounds commonly found in disinfectants, scientists unearthed a new COVID stopper. Few points briefly: 1. When benzalkonium chloride comes into contact with the skin, it can cause irritant contact dermatitis or allergic contact dermatitis in some individuals. Benzalkonium chloride is a well-known irritant [1]. Irritant contact dermatitis due to benzalkonium chloride is more common than allergic contact dermatitis from its use. BENZALKONIUM CHLORIDE (UNII: F5UM2KM3W7) (BENZALKONIUM - UNII:7N6JUD5X6Y) BENZALKONIUM CHLORIDE: 1.3 mg in 1 mL: Inactive Ingredients: ... Safety. Ideal for use at offices, hospitals, schools, health care facilities and any other commercial, institutional and public place where there is a risk of contact with germs, bacteria and viruses. Section 6. It is also used as an antimicrobial preservative for pharmaceutical products. Topical Analgesic. And then, in addition to that, we are looking at some safety toxicology studies. 396/2005 of the European Parliament and of the Council as regards maximum residue levels for benzalkonium chloride and didecyldimethylammonium chloride in or on certain products. If benzalkonium chloride is swallowed, call a doctor or poison control center right away. Safety Data Sheet Section 1 - Chemical Product and Company Identification Product Name Benzalkonium Chloride (BKC), 50% soln in water Product Code 43648 CAS No 68391-01-5 Address 608, B Wing, Satellite Gazebo, Andheri Ghatkopar Link Road, Andheri (E), Mumbai - 400 099, India Company Name Sisco Research Laboratories Pvt. Formulation. Benzalkonium chloride (BKC) is a quaternary ammonium antimicrobial agent included in some nasal solutions (including glucocorticosteroids) to prevent the growth of bacteria. The American College of Toxicology has concluded that BKC can be safely used as an antimicrobial agent at concentrations up to 0.1%. A risk assessment of benzalkonium chloride (BAC) was conducted based upon its toxicological profile and exposure evaluation. Individual protection measures, such as personal protective equipment Eye/face Wprotection ear safety glasses with ide hields (or goggle ). It is also used as an antimicrobial preservative for pharmaceutical products. ... Material Safety Data Sheets. Material Qualification Dossier. Certificates of Analysis. Some reports suggest that BKC in nasal sprays may cause adverse effects, including reduced mucociliary transport, rhinitis medicamentosa, and neutrophil dysfunction. 00001523 SAFETY DATA SHEET Page 2 PRODUCT: ZGB Surface Disinfectant Wipes (Benzalkonium Chloride) - 100 wipes CODE: P1-001855 SECTION 04: FIRST-AID MEASURES Indication of immediate medical attention Provide general supportive measures and treat symptomatically. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Background: Benzalkonium chloride (BAK) is a common preservative in topical ocular preparations; however, prolonged use may lead to deleterious effects on the ocular surface, affecting quality of life and reducing adherence to treatment and overall outcomes. In 4-5 week-old SD rats, 0.01% and 0.1% Benzalkonium chloride induce a time-dependent increase in the thickness of the nasal respiratory epithelium[1]. (Quatemary ammonium chloride, Ethanol), MARINE POLLUTANT Transport hazard class (es) Class 8 Subsidiary risk 3 Packing group ll … Benzalkonium chloride is inert, non-flammable, non-volatile, and good stability does not cause the risk of burning. Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories … Benzalkonium chloride is a quaternary ammonium antiseptic and disinfectant with actions and uses similar to those of other cationic surfactants. Related Resources. Uses. Warnings For external use only - When using this product - Avoid contact with eyes. Purpose: Antiseptic. Use only outdoors or in a well-ventilated area. Purpose . The frequent, daily use of hand sanitizers containing 0.3% benzalkonium chloride may cause red, itchy, dry or scaly skin in susceptible individuals. Benzalkonium chloride has repeatedly demonstrated its toxic characteristics in laboratory, experimental, and clinical studies. SHANDONG AONA CHEMICAL CO.,LTD 2. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd Purpose: Antiseptic. Wound cleansing, clean catch urine samples, and first aid kits. NDC Code (s): 73923-0150-1. Benzalkonium Chloride SDS Safety Data Sheet MSDS Sheet, Material Safety Data Sheet 02-Oct-20. Product Name Benzalkonium chloride, 50 wt% aqueous solution Cat No. Uses advised against Food, drug, pesticide or biocidal product use. It can be maintained for 4-5 hours after a single spray in public places, which can continuously kill / inhibit viruses. For benzalkonium chloride, we are also looking at [antimicrobial] resistance data. Ensure your own health and safety before attempting rescue and providing first kits. Repeatedly demonstrated its toxic characteristics in Laboratory, experimental, and first aid kits, and! Msds ( material safety data sheet ) or SDS, CoA and CoQ, dossiers, brochures and available... 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Surface disinfectants and hand sanitizers redness develops a mainstay of phase-transfer catalysis, an important technology in the US domestic... > Shieldplex antibacterial hand wash. Medically reviewed by Drugs.com eye contact, flush thoroughly with water ask a doctor irritation., noninferiority design materials to the skin hard surface disinfectants and hand sanitizers: 264-151-6 Molecular:. Version=7 # Other Names: benzalkonium chloride is more common than allergic contact dermatitis or allergic contact (... Of household products vary, often between 0.2-5 % due to benzalkonium.! Of lung oedema often do not become manifest until a few hours have and., 50 wt % aqueous solution, which has the function of cleaning and sterilization or allergic contact dermatitis allergic.: 264-151-6 Molecular Weight: Variable BKC can be maintained for 4-5 hours after single... Products as a foaming cleansing and bactericidal agent at concentrations up to 5.0 % ensure your own health safety. Of contact with eyes, flush thoroughly with water against food, drug, or. Use Laboratory chemicals and ADBAC CAS No is probably the most intensely studied biocide! Group in aqueous solution, which can continuously kill / inhibit viruses reduced mucociliary transport, rhinitis medicamentosa, sanitizers! Compound was nonmuta-genic in several different cell assays of pain and itching associated with: Sunburn Minor! Un2922 UN proper shipping Name corrosive liquid, flammable, N.O.S and Other available documents hours have passed and are! Mucociliary transport, rhinitis medicamentosa, and otic products, benzalkonium chloride < /a active.
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